Mad World sold well, for a ultra-violent game made in B&W. It was made for a niche market, you should know.
No More Heroes sold much better than Mad World (it is even getting a sequel), as a weird looking ultra-violent game in colour.
Zack & Wiki was poorly marketed by Capcom. Superficially, it looks like a kids' title but it is too complex for kids.
Dead Space was not announced enough and there is too many rail shooters in the market.
The Conduit is not exactly a great title, despite what many of the fans say.
Boom Box did very well, even got a sequel, despite the fact EA choose not to announce it.
In the other hand, check out games that received a good marketing campaign and already have some brand awareness: Rock Band, Guitar Hero, Sonic, Call of Duty, Resident Evil, among others. They are all good sellers in the Wii. It is true that most hardcore games prefer the hd consoles and thus the games made for this niche sell better in the PS3 and the 360, but they aren't the only good titles being produced nowadays.
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