Space Bust-a-Move is the latest iteration in the long running Bust-a-Move puzzle franchise (also sometimes known as Puzzle Bobble), and continues the series' tradition of having you fire colored bubbles towards other bubbles on the screen in the hopes of matching three (or more) like colors and thus eliminating those bubbles from the screen.
Players may choose to use stylus controls, in which you aim the launcher by dragging the stylus on the touch screen and click the bubble to launch it, or use traditional button controls, in which you'll simply aim your shot by using the directional pad of the Nintendo DS and then press a button to fire the bubble. In addition to standard bubbles of varying colors, you'll also encounter a handful of special bubbles, including bomb bubbles (that pop any other bubbles they touch) and line bubbles, which remove all bubbles from the line it touched. You'll be given bubbles of different colors and types to use in each stage, and it's up to you to make best use of what you've got to clear the screen and progress to later levels.