Destructoid: Without a doubt, Immortal Defense is one of the best tower defense games in existence. It addresses two major concerns people tend to have with the genre: lack of a compelling narrative, and boredom caused by passive sit-back-and-watch mechanics.
DIYGamer: "Taking a page out of Jason Rohrer’s book, story-driven tower defense title Immortal Defense is going pay what you want effective immediately."
Game Vortex writes: "I normally don't go for browser-based games. In fact, I try to avoid them as much as I can. It's not that I have anything against them, but they typically can't hold my attention for more than a few seconds. But, when it comes to browser-based games, Immortal Empire is a horse of a different color."
Tower defense games follow a pretty predictable formula; build turrets, fend off waves of encroaching enemies, rinse and repeat. Radical Poesis Games and Creations' Immortal Defense doesn't really deviate from this formula, but it still stands out from the crowd by virtue of its original presentation and strikingly imaginative science fiction story.